{"id":3088,"date":"2020-08-25T17:35:19","date_gmt":"2020-08-25T09:35:19","guid":{"rendered":"https:\/\/geneusmtc.com\/?p=3088"},"modified":"2020-08-25T17:37:21","modified_gmt":"2020-08-25T09:37:21","slug":"%e7%ba%96%e7%b6%ad%e8%82%8c%e7%97%9b%e7%97%87%e8%88%87comt%e5%8f%8agch1%e5%9f%ba%e5%9b%a0","status":"publish","type":"post","link":"https:\/\/geneusmtc.com\/%e7%ba%96%e7%b6%ad%e8%82%8c%e7%97%9b%e7%97%87%e8%88%87comt%e5%8f%8agch1%e5%9f%ba%e5%9b%a0\/","title":{"rendered":"\u7e96\u7dad\u808c\u75db\u75c7\u8207COMT\u53caGCH1\u57fa\u56e0"},"content":{"rendered":"<p><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-1 nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"background-color: rgba(255,255,255,0);background-position: left top;background-repeat: no-repeat;padding-top:100px;padding-right:0px;padding-bottom:75px;padding-left:0px;margin-bottom: 0px;margin-top: 0px;border-width: 0px 0px 0px 0px;border-color:#eae9e9;border-style:solid;\" ><div class=\"fusion-builder-row fusion-row\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-0 fusion_builder_column_1_1 1_1 fusion-one-full fusion-column-first fusion-column-last\" style=\"margin-top:0px;margin-bottom:0px;\"><div class=\"fusion-column-wrapper fusion-flex-column-wrapper-legacy\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;background-color:#ffffff;border-width: 0px 0px 0px 0px;border-color:#dddddd;border-style:solid;padding: 0px 20px 0px 20px;\"><div class=\"fusion-text fusion-text-1\"><h2>\u7e96\u7dad\u808c\u75db\u75c7\u8207<em>COMT<\/em>\u53ca<em>GCH1<\/em>\u57fa\u56e0<\/h2>\n<\/div><div class=\"fusion-text fusion-text-2\"><p>\u5076\u50cf\u5718\u9ad4F4\u7684\u6210\u54e1\u4e4b\u4e00\u6731\u5b5d\u5929\uff0c\u8fd1\u5e74\u4f86\u591a\u6578\u6642\u9593\u90fd\u5728\u5927\u9678\u767c\u5c55\uff0c\u96e3\u5f97\u6700\u8fd1\u6709\u7a7a\u5728\u53f0\u7063\u9732\u81c9\uff0c\u4ed6\u5766\u8a00\u7d50\u5a5a4\u5e74\u9072\u9072\u6c92\u6709\u5c0f\u5b69\u7684\u539f\u56e0\u5c31\u662f\u56e0\u70ba\u81ea\u5df1\u7f79\u60a3\u7e96\u7dad\u808c\u75db\u75c7\uff0c\u4e5f\u5c31\u662f\u4fd7\u7a31\u7684\u516c\u4e3b\u75c5\u6216\u738b\u5b50\u75c5\uff0c\u800c\u76ee\u524d\u4e5f\u9084\u6c92\u8fa6\u6cd5\u505a\u57fa\u56e0\u6aa2\u6e2c\uff0c\u56e0\u6b64\u66ab\u6642\u4e0d\u6562\u6709\u5c0f\u5b69\u3002<sup>1<\/sup><\/p>\n<p>\u5230\u5e95\u4ec0\u9ebc\u662f\u7e96\u7dad\u808c\u75db\u75c7\u5462? \u7e96\u7dad\u808c\u75db\u75c7\u539f\u540dFibromyalgia\uff0c\u662f\u4e00\u7a2e\u6162\u6027\u64f4\u6563\u6027\u75bc\u75db\uff0c\u60a3\u8005\u5c0d\u89f8\u78b0\u7684\u58d3\u529b\u53cd\u61c9\u611f\u53d7\u5f37\u70c8\uff0c\u5176\u4ed6\u75c7\u72c0\u5305\u62ec\u75b2\u5026\u3001\u7761\u7720\u969c\u7919\u4ee5\u53ca\u8a18\u61b6\u969c\u7919\u7b49\u3002\u7e96\u7dad\u808c\u75db\u75c7\u7d04\u4f54\u7e3d\u4eba\u53e3\u76842\u20138%\uff0c\u5168\u7403\u7684\u76db\u884c\u7387\u90fd\u5dee\u4e0d\u591a\uff0c\u6027\u5225\u65b9\u9762\uff0c\u5973\u6027\u8f03\u7537\u6027\u70ba\u591a\u3002<sup>2<\/sup><\/p>\n<p>\u7e96\u7dad\u808c\u75db\u75c7\u7684\u75c5\u7406\u6a5f\u8f49\u76ee\u524d\u9084\u4e0d\u751a\u6e05\u695a\u3002\u4f9d\u64da\u7f8e\u570b\u570b\u5bb6\u885b\u751f\u9662\u5c0d\u65bc\u7e96\u7dad\u808c\u75db\u75c7\u7684\u4e86\u89e3\uff0c\u9019\u7a2e\u75c5\u7665\u901a\u5e38\u6709\u5bb6\u65cf\u907a\u50b3\u6027\uff0c<sup>3<\/sup>\u5728\u570b\u5167\u5f70\u5316\u57fa\u7763\u6559\u91ab\u9662\u548c\u5f18\u5149\u79d1\u6280\u5927\u5b78\u7684\u5171\u540c\u7814\u7a76\u4e2d\u4e5f\u8a8d\u70ba\u81e8\u5e8a\u8a55\u4f30\u53ca\u8a3a\u65b7\u65b9\u6cd5\uff0c\u56e0\u5e38\u8207\u5176\u4ed6\u514d\u75ab\u53ca\u7cbe\u795e\u75be\u75c5\u4f75\u5b58\uff0c\u800c\u5c0e\u81f4\u8a3a\u65b7\u4e0a\u7684\u56e0\u96e3\u3002<sup>4<\/sup><\/p>\n<p>\u4f9d\u64da\u7f8e\u570b\u671f\u520aJournal of Translational Medicine 2018\u5e74\u767c\u8868\u7684\u4e00\u7bc7\u6587\u7ae0\uff0c\u767c\u73fe\u4e00\u500b\u4f4d\u65bc<em>COMT<\/em>\u7684\u8b8a\u7570\u9eders2097903\u8207\u4f4d\u65bc<em>GCH1<\/em>\u7684\u8b8a\u7570\u9eders841\u6240\u9020\u6210\u7684\u516c\u4e3b\u75c5\u5c31\u662f\u8207\u7e96\u7dad\u808c\u75db\u75c7\u6709\u95dc\u3002<sup>5<\/sup><\/p>\n<p><em>\u00a0\u00a0\u00a0 COMT<\/em>\u57fa\u56e0\u88fd\u9020\u5152\u8336\u915a-O-\u7532\u57fa\u8f49\u79fb\u9176\u7684\u9175\u7d20\uff0c\u5728\u5927\u8166\u4e2d\uff0c\u9019\u7a2e\u9175\u7d20\u6709\u52a9\u65bc\u5206\u89e3\u795e\u7d93\u905e\u8cea\u7269\u8cea\uff0c\u9019\u4e9b\u6771\u897f\u53ef\u5c07\u4fe1\u865f\u5f9e\u4e00\u500b\u795e\u7d93\u7d30\u80de\u50b3\u5c0e\u5230\u53e6\u4e00\u500b\u3002\u6b64\u9175\u7d20\u5728\u5927\u8166\u524d\u984d\u8449\u76ae\u5c64\u7684\u5340\u57df\u7279\u5225\u91cd\u8981\uff0c\u53ef\u7d44\u7e54\u548c\u5354\u8abf\u4f86\u81ea\u5927\u8166\u5176\u4ed6\u90e8\u4f4d\u7684\u4fe1\u606f\u3002\u8a72\u5340\u57df\u6d89\u53ca\u4eba\u683c\u3001\u8a08\u5283\u3001\u884c\u70ba\u6291\u5236\u3001\u62bd\u8c61\u601d\u7dad\u3001\u60c5\u611f\u548c\u5de5\u4f5c\uff08\u77ed\u671f\uff09\u8a18\u61b6\u7b49\u3002<sup>6<\/sup><\/p>\n<p><em>\u00a0\u00a0\u00a0 GCH1<\/em>\u57fa\u56e0\u88fd\u9020\u7684\u9175\u7d20\u53c3\u8207\u751f\u7522\u56db\u6c2b\u751f\u7269\u8776\u5464\uff08BH4\uff09\u800cBH4\u53c3\u8207\u795e\u7d93\u50b3\u905e\u7269\u8cea-\u591a\u5df4\u80fa\u548c\u8840\u6e05\u7d20\u7684\u5169\u7a2e\u795e\u7d93\u905e\u8cea\u7684\u88fd\u9020\u3002\u591a\u5df4\u80fa\u6703\u5728\u5927\u8166\u5167\u50b3\u905e\u4fe1\u865f\u4ee5\u7522\u751f\u5e73\u7a69\u7684\u8eab\u9ad4\u904b\u52d5\uff0c\u800c\u8840\u6e05\u7d20\u5247\u8abf\u7bc0\u60c5\u7dd2\u3001\u60c5\u611f\u3001\u7761\u7720\u548c\u98df\u617e\u3002\u4e5f\u5c31\u662f\u8aaa<em>COMT<\/em>\u548c<em> GCH1<\/em>\u90fd\u8207\u5927\u8166\u5167\u7684\u795e\u7d93\u7269\u8cea\u50b3\u5c0e\u6709\u95dc\uff0c<sup>7<\/sup>\u6240\u4ee5\u9019\u5169\u500b\u57fa\u56e0\u7684\u8b8a\u7570\u8207\u7e96\u7dad\u808c\u75db\u75c7\u6709\u95dc\u806f\u662f\u53ef\u60f3\u800c\u77e5\u7684\uff0c\u9019<em>COMT<\/em>\u548c<em> GCH1<\/em>\u7684\u57fa\u56e0\u8b8a\u7570\u7686\u53ef\u5728\u6676\u6e96\u91ab\u5b78\u79d1\u6280\u516c\u53f8\u7684\u5168\u57fa\u56e0\u6aa2\u6e2c\u4e2d\u5206\u6790\u51fa\u4f86\u3002<\/p>\n<p>#\u7e96\u7dad\u808c\u75db\u75c7 #<em> COMT<\/em>#<em> GCH1<\/em>#\u57fa\u56e0\u6aa2\u6e2c #\u5168\u57fa\u56e0\u6aa2\u6e2c<\/p>\n<p><img decoding=\"async\" class=\"alignnone size-full wp-image-3090\" src=\"https:\/\/geneusmtc.com\/wp-content\/uploads\/2020\/08\/AdobeStock_263690400-1-scaled-e1598348013503.jpeg\" alt=\"\" width=\"800\" height=\"500\" \/><\/p>\n<p>\u53c3\u8003\u8cc7\u6599\uff1a<\/p>\n<ol>\n<li><a href=\"https:\/\/tw.stock.yahoo.com\/news\/%E7%94%B7%E6%98%9F%E7%BD%B9%E7%BD%95%E7%97%85%E5%85%A8%E8%BA%AB%E7%97%9B-%E5%98%86-%E7%84%A1%E6%B3%95%E8%87%AA%E4%B8%BB%E5%BE%A9%E5%8E%9F-%E9%99%A4%E4%BA%86%E9%81%BA%E5%82%B3%E9%82%84%E6%9C%893%E5%A4%A7%E8%82%87%E5%9B%A0-060000802.html\">https:\/\/tw.stock.yahoo.com\/news\/%E7%94%B7%E6%98%9F%E7%BD%B9%E7%BD%95%E7%97%85%E5%85%A8%E8%BA%AB%E7%97%9B-%E5%98%86-%E7%84%A1%E6%B3%95%E8%87%AA%E4%B8%BB%E5%BE%A9%E5%8E%9F-%E9%99%A4%E4%BA%86%E9%81%BA%E5%82%B3%E9%82%84%E6%9C%893%E5%A4%A7%E8%82%87%E5%9B%A0-060000802.html<\/a><\/li>\n<li><a href=\"https:\/\/www.wikiwand.com\/zh-hk\/%E7%BA%A4%E7%BB%B4%E8%82%8C%E7%97%9B\">https:\/\/www.wikiwand.com\/zh-hk\/%E7%BA%A4%E7%BB%B4%E8%82%8C%E7%97%9B<\/a><\/li>\n<li><a href=\"https:\/\/ghr.nlm.nih.gov\/condition\/fibromyalgia#genes\">https:\/\/ghr.nlm.nih.gov\/condition\/fibromyalgia#genes<\/a><\/li>\n<li><a href=\"https:\/\/docsplayer.com\/108391637-%E6%BE%84-%E6%B8%85-%E9%86%AB-%E8%AD%B7-%E7%AE%A1-%E7%90%86-%E9%9B%9C-%E8%AA%8C-cheng-ching-medical-journal-%E5%8F%8A%E5%A4%9A%E7%99%BC%E6%80%A7%E8%82%8C%E8%82%89%E6%80%A7%E7%9A%84%E5%A3%93%E7%97%9B%E9%BB%9E-%E4%BA%A6%E5%8F%AF%E8%83%BD%E4%BC%B4%E9%9A%A8%E6%9C%89%E5%85%B6%E4%BB%96%E7%9B%B8%E9%97%9C%E7%97%87-%E8%A1%8C%E8%A9%95%E4%BC%B0-%E6%9C%80%E9%AB%98%E7%A9%8D%E5%88%86%E7%82%BA31%E5%88%86-%E7%95%B6%E7%B5%90%E6%9E%9C%E7%82%BAwpi-7-ss-5%E6%88%96-%E7%8B%80-%E5%A6%82%E7%96%B2%E5%8B%9E-%E7%9D%A1%E7%9C%A0%E4%B8%8D%E8%B6%B3%E6%88%96-%E5%8F%8A%E8%AA%8D%E7%9F%A5%E5%8A%9F%E8%83%BD%E9%9A%9C%E7%A4%99-%E8%A8%B1%E5%A4%9A%E7%97%85-wpi-3-6-ss-9-%E5%8D%B3%E5%8F%AF%E8%A8%BA%E6%96%B7%E7%82%BAfm-%E5%A6%82%E5%9C%96%E4%B8%80-7.html\">https:\/\/docsplayer.com\/108391637-%E6%BE%84-%E6%B8%85-%E9%86%AB-%E8%AD%B7-%E7%AE%A1-%E7%90%86-%E9%9B%9C-%E8%AA%8C-cheng-ching-medical-journal-%E5%8F%8A%E5%A4%9A%E7%99%BC%E6%80%A7%E8%82%8C%E8%82%89%E6%80%A7%E7%9A%84%E5%A3%93%E7%97%9B%E9%BB%9E-%E4%BA%A6%E5%8F%AF%E8%83%BD%E4%BC%B4%E9%9A%A8%E6%9C%89%E5%85%B6%E4%BB%96%E7%9B%B8%E9%97%9C%E7%97%87-%E8%A1%8C%E8%A9%95%E4%BC%B0-%E6%9C%80%E9%AB%98%E7%A9%8D%E5%88%86%E7%82%BA31%E5%88%86-%E7%95%B6%E7%B5%90%E6%9E%9C%E7%82%BAwpi-7-ss-5%E6%88%96-%E7%8B%80-%E5%A6%82%E7%96%B2%E5%8B%9E-%E7%9D%A1%E7%9C%A0%E4%B8%8D%E8%B6%B3%E6%88%96-%E5%8F%8A%E8%AA%8D%E7%9F%A5%E5%8A%9F%E8%83%BD%E9%9A%9C%E7%A4%99-%E8%A8%B1%E5%A4%9A%E7%97%85-wpi-3-6-ss-9-%E5%8D%B3%E5%8F%AF%E8%A8%BA%E6%96%B7%E7%82%BAfm-%E5%A6%82%E5%9C%96%E4%B8%80-7.html<\/a><\/li>\n<li><a href=\"https:\/\/translational-medicine.biomedcentral.com\/articles\/10.1186\/s12967-018-1416-8#Tab1\">https:\/\/translational-medicine.biomedcentral.com\/articles\/10.1186\/s12967-018-1416-8#Tab1<\/a><\/li>\n<li><a href=\"https:\/\/ghr.nlm.nih.gov\/gene\/COMT\">https:\/\/ghr.nlm.nih.gov\/gene\/COMT<\/a><\/li>\n<li><a href=\"https:\/\/ghr.nlm.nih.gov\/gene\/GCH1\">https:\/\/ghr.nlm.nih.gov\/gene\/GCH1<\/a><\/li>\n<\/ol>\n<\/div><div class=\"fusion-clearfix\"><\/div><\/div><\/div><\/div><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-2 fusion-parallax-fixed nonhundred-percent-fullwidth non-hundred-percent-height-scrolling fusion-equal-height-columns\" style=\"background-color: rgba(255,255,255,0);background-image: url(&quot;https:\/\/geneusmtc.com\/wp-content\/uploads\/2015\/12\/make-an-appointment.jpg&quot;);background-position: center center;background-repeat: no-repeat;padding-top:110px;padding-right:0px;padding-bottom:100px;padding-left:0px;margin-bottom: 0px;margin-top: 0px;border-width: 0px 0px 0px 0px;border-color:#eae9e9;border-style:solid;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;background-attachment:fixed;\" ><div class=\"fusion-builder-row fusion-row\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-1 fusion_builder_column_3_5 3_5 fusion-three-fifth fusion-column-first\" style=\"width:58.4%; margin-right: 4%;margin-top:0px;margin-bottom:30px;\"><div class=\"fusion-column-wrapper fusion-flex-column-wrapper-legacy\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div class=\"fusion-text fusion-text-3\"><h2 class=\"fusion-responsive-typography-calculated\" data-fontsize=\"48\" data-lineheight=\"60px\" data-fusion-font=\"true\"><span style=\"color: #ffffff;\">\u806f\u7d61\u6676\u6e96<\/span><\/h2>\n<\/div><div class=\"fusion-text fusion-text-4\"><p><span style=\"color: #ffffff;\" data-fusion-font=\"true\">\u5c0d\u65bc\u6211\u5011\u7684\u7522\u54c1\u8cc7\u8a0a\u9084\u6709\u7591\u60d1\u55ce\uff1f<\/span><\/p>\n<p><span style=\"color: #ffffff;\" data-fusion-font=\"true\">\u6b61\u8fce\u8a62\u554f\u6211\u5011\u5c08\u696d\u7684\u91ab\u5b78\u5ba2\u670d\u5c08\u54e1\uff0c\u6211\u5011\u6703\u76e1\u5feb\u8207\u60a8\u806f\u7d61\u3002<\/span><\/p>\n<\/div><div class=\"fusion-clearfix\"><\/div><\/div><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-2 fusion_builder_column_2_5 2_5 fusion-two-fifth fusion-column-last\" style=\"width:37.6%;margin-top:0px;margin-bottom:30px;\"><div class=\"fusion-column-wrapper fusion-flex-column-wrapper-legacy\" style=\"background-position:left 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